endogenous opioid system
5 episodes mention this concept
DrTraceyMarksMar 25, 2026Why You Pull Away After Getting Close: Understanding Relational Satiation and Neurobiological Thresholds
RelationshipsRelational SatietyNeurobiological ThresholdHomeostasisDopamine System
DocSnipesMar 13, 2025The Overlap of CPTSD and BPD: Trauma, Diagnosis, and Neurobiological Insights
PsychologyComplex Post-Traumatic Stress Disorder (CPTSD)Borderline Personality Disorder (BPD)Adverse Childhood Experiences (ACEs)Attachment Disruption
hubermanlabJul 28, 2023Kratom: Risks, Addiction Potential, and Opioid Mechanisms
HealthKratom (Mitragyna speciosa)Opioid crisisAddictionHabit-forming- DocSnipesApr 10, 2021
CBD, Chronic Pain Management, and Opioid Reduction: Mechanisms and Efficacy
HealthChronic non-cancer painOpioid reductionInflammatory responseSerotonin receptors - DocSnipesJan 21, 2021
The Complex Interplay of Hormones and Neurotransmitters in Mood and Behavioral Health
HealthNeurotransmitter families and receptor subtypes (e.g., 5HT1-7)Excitatory vs. Inhibitory NeurotransmittersHPA Axis (Hypothalamic-Pituitary-Adrenal Axis)Excitotoxicity (Glutamate)
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Related concepts
Concepts that appear alongside endogenous opioid system across episodes.
- dopamine system
- sedative effect
- neurotransmitter imbalance (dopamine, serotonin)
- decoupling (dopamine-opioid mismatch)
- oxidative stress
- prefrontal cortex (pfc)
- peripheral neuropathy
- attachment disruption
- complex post-traumatic stress disorder (cptsd)
- gut motility / gut-brain axis
- mu-opioid receptor
- kratom (mitragyna speciosa)
- endorphin resistance
- addiction
- thyroid resistance (thyroxine resistance)
- neurological dysfunction
- opioid reduction
- neurobiological threshold
- chronic non-cancer pain
- trust vs. mistrust (eriksonian stage)