brain-derived neurotrophic factor
48 episodes mention this concept
DocSnipesMar 18, 2026Physiological and Diagnostic Challenges of Addiction in Aging Adults
HealthCellular Age vs. Chronological AgePharmacokineticsDrug Half-lifeLiver and Kidney Clearance
drekbergMar 13, 202610 Daily Habits That Silently Accelerate Brain Damage and Dementia
HealthType 3 Diabetes (Alzheimer's as metabolic disease)Insulin ResistanceAdvanced Glycation End Products (AGEs)Neuroinflammation
hubermanlabJan 15, 2026Essentials: The Neuroscience of Memory, Attention, and Brain Health Through Exercise with Dr. Wendy Suzuki
NeuroscienceMemory encodingNovelty (memory)Repetition (memory)Association (memory)- drekbergOct 3, 2025
Optimizing Turmeric Absorption: Unlocking Cellular Benefits with Fenugreek Colloid vs. Traditional Use
HealthBioavailabilityXenobioticFirst-pass metabolismConjugation - hubermanlabMay 22, 2025
Optimizing Daily Physiology: Huberman Lab's Science-Based Protocols for Enhanced Health and Performance
HealthCircadian RhythmsTemperature MinimumForward AmbulationOptic Flow - hubermanlabMay 19, 2025
The Science & Art of Comedy & Creativity with Tom Segura
ScienceNeuroscience of humorPsychology of comedyCreative processReward circuits (brain) 
HealthyGamerGGApr 15, 2025Psychedelics: How to Edit Your Brain - A Psychiatrist's Nuanced Perspective on Efficacy and Safety
PsychologyPsychedelics (class of compounds)Serotonin 2A receptor (5HT2A receptor)NeuroplasticityNeurogenesis- drekbergFeb 28, 2025
What Happens During a 100-Hour Water Fast: Benefits, Physiology, and Practical Guidance
HealthGlycogen depletion phaseAutophagyInsulin sensitivityGluconeogenesis - DocSnipesFeb 12, 2025
Revolutionary New Treatment Strategies for Depression: TMS, Anti-inflammatory Approaches, and Gut Microbiome
HealthTranscranial Magnetic Stimulation (TMS)NeuromodulationDorsal Lateral Prefrontal Cortex (DLPFC)Subgenual Anterior Cingulate Cortex 
DrTraceyMarksJan 15, 2025How Exercise Rewires Your Brain for Better Mental Wellbeing: Structural Changes and Practical Tips
HealthNeurogenesisHippocampusPrefrontal cortexBrain-Derived Neurotrophic Factor (BDNF)- DocSnipesDec 22, 2024
The Neurochemical Basis of Pornography Addiction, Withdrawal, and Recovery
NeuroscienceNeurochemical processCompulsive sexual behavior disorder (CSBD)HPA axis (Hypothalamic-Pituitary-Adrenal axis)Andro accelerator hypothesis - HealthyGamerGGAug 7, 2024
The Self-Brainwashing Epidemic: How Digital Echo Chambers Erode Cognitive Flexibility and Mental Health
PsychologySelf-brainwashingCognitive flexibilityBrain-derived neurotrophic factor (BDNF)Echo chambers - HealthyGamerGGMay 29, 2024
Why Your Sleep Habits Aren't Healthy: Fixing Sleep by Optimizing Waking Hours and Daily Life
HealthSleep hygieneCircadian rhythmAdenosineFrontal lobes - DrTraceyMarksApr 10, 2024
Psychedelic Progress: LSD-Derived M-120 Fast-Tracked for Generalized Anxiety Disorder Treatment
HealthBreakthrough Therapy StatusGeneralized Anxiety Disorder (GAD)Lysergic Acid Diethylamide (LSD)M-120 (LSD-derived drug) - HealthyGamerGGMar 30, 2024
The Neuroscientific Link Between ADHD and Obesity: Mechanisms and Interventions
PsychologyMind-Body ConnectionAltered Reward ProcessingDopaminergic CircuitryPrefrontal Cortex (PFC) - drekbergMar 29, 2024
What REALLY Happens When You Start EXERCISING Every Day For 30 Days: The Brain-Body Connection and Holistic Health Benefits
HealthExercise as a holistic health driverBrain's primary purpose (movement management)Energy expenditure of the brainSea squirt (biological example) - hubermanlabMar 22, 2024
Optimizing Brain Health and Cognitive Function: Protocols for Longevity, Willpower, and Circadian Rhythm Management
HealthZone 2 cardioBrain-derived neurotrophic factor (BDNF)Anti-inflammatory cytokinesNeurodegeneration - DocSnipesFeb 21, 2024
Navigating Post-Acute Withdrawal Syndrome (PAWS) in Pornography Addiction Recovery
PsychologyPost-Acute Withdrawal Syndrome (PAWS)Delta FosBHormone and Neurotransmitter ImbalancesDopamine Receptors - drekbergFeb 9, 2024
What Happens During a 100-Hour Fast: Unlocking Metabolic Health and Longevity
HealthExtended FastingIntermittent FastingAutophagyInsulin Sensitivity - DrTraceyMarksFeb 7, 2024
Spravato vs. Seroquel: Ketamine's Superiority in Treatment-Resistant Depression and Expanding Formulations
HealthKetamineTreatment-resistant depression (TRD)NMDA receptor antagonistNeuroplasticity - DrTraceyMarksJan 17, 2024
Navigating Antidepressant Treatment: Understanding Emotional Numbness, Mechanisms, and Realistic Expectations
HealthEmotional numbnessApathyReduced emotional reactivityNeurotransmitters - DrTraceyMarksOct 11, 2023
Behavioral Activation: The Hidden Weapon Against Depression Explained
PsychologyDepressionBehavioral Activation (BA)Negative Feedback LoopPsychological Reward - hubermanlabAug 7, 2023
Ketamine: Clinical Benefits, Risks, Mechanisms, and Neuroplasticity for Depression, PTSD, and Suicidality
HealthKetamineDissociative statesK-holeNeuroplasticity - drekbergFeb 24, 2023
Preventing Dementia: Expert Tips on Frontotemporal Dementia, Brain Fuel, and Lifestyle Interventions
HealthFrontotemporal Dementia (FTD)AphasiaAlzheimer's DiseaseFrontal Lobe - DrTraceyMarksJan 25, 2023
Ketamine's Role in the Psychedelic Revolution: Mechanisms, Forms, and Accessibility for Mental Health Treatment
HealthPsychedelicsMDMA (Ecstasy)Psilocybin (Mushrooms)Ketamine (Special K) - drekbergJan 13, 2023
Activating Autophagy for Longevity: The Science of Exercise and Fasting for Optimal Health
HealthAutophagyHypoxiaMisfolded proteinsProtein aggregates - drekbergOct 7, 2022
The 30-Day Sugar Elimination Challenge: Unlocking Metabolic Health and Longevity
HealthSugar addictionBlood sugar regulationInsulin responseHypoglycemia - DrTraceyMarksSep 28, 2022
Four Underrated Tools for Anxiety: Diet, Intermittent Fasting, Mindfulness, and Deep Pressure Touch
HealthProcessed foodsInflammationHigh fructose corn syrupIntermittent fasting - DocSnipesJul 18, 2022
Intermittent Fasting: Resetting Circadian Rhythms, Reducing Inflammation, and Boosting Mental Health
HealthIntermittent Fasting (IF)Circadian RhythmsKetones / KetogenesisGlucose to Ketone Switchover / Intermittent Metabolic Switching - DocSnipesMay 17, 2022
How Exercise Boosts Mental Health: Increasing Serotonin, Dopamine, and Reducing Inflammation
HealthOxygenationVagal toneHeart Rate Variability (HRV)Catharsis - drekbergApr 15, 2022
The Absolute Best Way to Reverse and Slow Dementia: Understanding Mechanisms and Actionable Steps
HealthDementia (multifactorial)NeuroinflammationMicroglia (priming, persistent activation)Blood-brain barrier - DrTraceyMarksNov 24, 2021
What Exercise Does To Your Brain: Endocannabinoids, Neurogenesis, and Mood Enhancement
HealthRunner's highEndorphinsEndocannabinoidsBlood-brain barrier - drekbergOct 8, 2021
The Profound Impact of Eliminating Sugar for 30 Days: Metabolic Health, Brain Function, and Addiction Reversal
HealthDisaccharidesPolysaccharides (Starch)GlucoseFructose - drekbergFeb 5, 2021
What Happens To Your Brain If You NEVER Exercise: Beyond Weight Loss
HealthInsulin resistanceMetabolic syndromeBrain degenerationNeuroplasticity - drekbergAug 21, 2020
Synergistic Benefits of Apple Cider Vinegar and Fasting for Metabolic Health and Longevity
HealthInsulin resistanceMetabolic syndromeDegenerative diseasesHuman Growth Hormone (HGH) - drekbergAug 7, 2020
What Happens When You Fast: Metabolic Shifts, Autophagy, and Hormonal Benefits
HealthFastingMetabolic flexibilityGlucose metabolismGlycogenolysis - drekbergApr 27, 2020
Debunking Belly Fat Myths: The Science of Aerobic Exercise, Insulin Resistance, and Hormonal Optimization for Natural Fat Loss
HealthBelly fat misinformationSubcutaneous fatVisceral fatInsulin resistance - drekbergApr 24, 2020
5 Intermittent Fasting Tips for Managing Ravenous Hunger and Enhancing Fat Adaptation
HealthIntermittent Fasting (IF)Time-Restricted EatingFasting WindowFeeding Window - DocSnipesApr 11, 2020
The Neurobiology of Addiction: Understanding Tolerance, Withdrawal, and Neurotransmitter Dysregulation
NeuroscienceToleranceWithdrawal symptomsPost-Acute Withdrawal Syndrome (PAWS)Homeostasis - drekbergDec 6, 2019
Ultimate Guide to Extreme Anti-Aging & Looking Young: 10 Ways to Reverse Aging Naturally and Prolong Vitality
HealthLoss of function (aging)Programmed agingToxicityDeficiency - drekbergOct 18, 2019
10 Intermittent Fasting Tips for Easy Success and Understanding Its Metabolic Benefits
HealthIntermittent FastingInsulin ResistanceAutophagyFat Adaptation - drekbergSep 30, 2019
High-Intensity Interval Training (HIIT): Understanding Its Hormonal Benefits, Proper Implementation, and Recovery for Optimal Health
HealthHigh-Intensity Interval Training (HIIT)Growth Hormone (GH)Brain-Derived Neurotrophic Factor (BDNF)Lactic Acid - drekbergJun 10, 2019
The 36+ Compelling Benefits of Intermittent Fasting for Metabolic Health, Longevity, and Disease Prevention
HealthIntermittent Fasting (IF)Insulin ResistanceBlood Glucose RegulationAutophagy (Self-eating) - DrTraceyMarksDec 12, 2018
Antidepressants Don't Shrink Your Brain, But Depression Does: Understanding the Neurobiological Impact and Protective Role of Treatment
HealthMajor depression (illness)Brain cell lossMagnetic Resonance Imaging (MRI)PET scans - drekbergAug 10, 2018
Debunking Sumo Wrestler Weight Gain: The Role of Carbs, Insulin Resistance, and Proper Intermittent Fasting
HealthIntermittent Fasting (IF)Insulin ResistanceFat AdaptationCarbohydrate Dependence - drekbergJul 9, 2018
How Stress Rewires Your Brain: Mechanisms, Hormones, and Interventions
NeuroscienceBrain cells (neurons)Neural networksSynapsesHypertrophy (cellular growth) - drekbergFeb 12, 2018
The Unique Benefits of High-Intensity Interval Training: Brain Stimulation, Circulation, and Hormonal Stress Response
HealthHigh-Intensity Interval Training (HIIT)Steady CardioNervous System ActivationCirculation - hubermanlab
The Biology, Psychology, and Utility of Play for Brain Plasticity and Lifelong Learning
NeurosciencePeriaqueductal Gray (PAG)Endogenous opioidsEnkephalinPrefrontal cortex